Raised ?2-Microglobulin as a Surrogate Marker in Non-Secretory Multiple Myeloma
نویسندگان
چکیده
منابع مشابه
urinary beta 2-microglobulin as a prognostic marker in children with pyelonephritis running title: beta 2-microglobulin a prognostic marker
background urinary tract infection (uti) is common in children. uti with or without vesico-ureteral reflux (vur) may result in renal scarring. severe renal scarring impairs renal function and may result in hypertension, renal insufficiency, and end stage renal disease requiring dialyses or transplantation. beta 2 micro-globulin (ß2mg) is a low molecular weight protein freely filtered by the glo...
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Multiple Myeloma is a neoplasm of B cell lineage characterized by excessive proliferation of abnormal plasma cells. It is characterized by a clinical pentad of 1) anemia, 2) a monoclonal protein in the serum or the urine or both, 3) bone leisons and or bone pain, 4) hypercalcemia >11.5g/dl and 5) renal insufficiency. Non secretory multiple myeloma is a rare variant of the classic form of multi...
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The spectrum of plasma cell neoplasm represents indolent conditions like Monoclonal Gammopathy of Undetermined Significance (MGUS) to more aggressive multiple myeloma and plasma cell leukemia. Non-secretory myeloma comprises less than 01% of this spectrum where serum protein electrophoresis and quantitative immunoglobulins remain essentially normal. We are presenting a case report of this rare ...
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A case of non-secretory multiple myeloma presenting as primary plasma cell leukaemia in a 65 year old woman is presented. Bone pain was the initial clinical manifestation. Laboratory analysis showed 20% of circulating immature plasma cells. Despite the presence of osteolytic lesions, no M-component could be demonstrated in serum protein electrophoresis, and serum and urine immunoelectrophoresis...
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We report a case of a 58-year-old woman with a true non secretory multiple myeloma of the producer type relapsing after many lines of therapy including the novel anti-myeloma drugs, which eventually relapsed as extramedullary liver plasmacytomas manifesting as a fatal acute cholestatic hepatitis. Due to the aggressiveness of this disease, new therapeutic modalities are necessary.
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ژورنال
عنوان ژورنال: Bangladesh Journal of Medical Science
سال: 2017
ISSN: 2076-0299,2223-4721
DOI: 10.3329/bjms.v16i1.31146